ASTRO Guideline Focused Update on Radiation Therapy for Rectal Cancer
Published: Web posted November 25, 2024
This guideline update addresses three key questions focusing on the appropriate indications and dose-fractionation regimens for neoadjuvant therapy, optimal sequencing of radiation therapy and systemic therapy in the context of total neoadjuvant therapy, and considerations for selective omission of radiation therapy and surgery for patients with rectal cancer. All recommendations are either new, modified or unchanged from the 2021 guideline, except for the KQ4 section which remains unchanged as there were no new practice-changing data. This guideline is a focused update of ASTRO’s original 2021 guideline on radiation therapy for rectal cancer.
Developed in collaboration with:
- American Society of Clinical Oncology
- Society of Surgical Oncology
Endorsed by:
- European Society for Radiotherapy and Oncology
- Royal Australian and New Zealand College of Radiologists
- Society of Surgical Oncology
Resources:
Previous/full guideline:
Radiation Therapy for Rectal Cancer: An ASTRO Clinical Practice Guideline - 2021
