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Guideline Development Process

Learn about ASTRO's clinical practice guideline development process from concept to publication.

Guideline Initiatives

See ASTRO's guidelines in development, including collaborations with other organizations, as well as a list of potential future topics.


Clinical Practice Guidelines

Guidelines are "Statements that include recommendations intended to optimize patient care that are informed by a systematic review of evidence and an assessment of the benefits and harms of alternative care options" as defined by the National Academy of Medicine (formerly Institute of Medicine).


Salvage Therapy for Prostate Cancer (AUA/ASTRO/SUO) – 2024 (coming soon)

Clinically Localized Prostate Cancer (AUA/ASTRO/SUO) – 2022

Treatment of Non-Metastatic Muscle-Invasive Bladder Cancer (AUA/ASCO/ASTRO/SUO) – Amended 2020, Original 2017

Adjuvant and Salvage Radiation Therapy After Prostatectomy (ASTRO/AUA) – 2018

Hypofractionation for Localized Prostate Cancer (ASTRO/ASCO/AUA) – 2018


Guidelines developed by other organizations where ASTRO is invited to participate may be considered for endorsement. ASTRO prefers to have one or more representatives on the task force, to peer review the draft guideline and then to receive a final version for endorsement consideration. All endorsed documents must be approved by ASTRO’s Board of Directors. See the collaborative guideline development page for more detail.

Guideline on Osteoradionecrosis in Patients with Head and Neck Cancer Treated with Radiation Therapy (ISOO-MASCC-ASCO)  – 2024

Management of Stage III Non-Small-Cell Lung Cancer Guideline (ASCO) – 2021; Read ASTRO's summary; ASTRO Podcast

Low-Dose-Rate (LDR) Brachytherapy for Primary Treatment of Localized Prostate Cancer: A Systemic Review and Executive Summary of an Evidence-Based Consensus Statement (ABS) – 2021

Advanced Prostate Cancer Guideline (AUA) – 2020; Amended 2023; Read ASTRO's editorial

Diagnosis and Treatment of Early Stage Testicular Cancer Guideline (AUA) – 2019

Autologous Breast Reconstruction with DIEP or Pedicled TRAM Abdominal Flaps Autologous Breast Reconstruction with DIEP or Pedicled TRAM Abdominal Flaps (ASPS) – 2017

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