Guideline Development Process
Learn about ASTRO's clinical practice guideline development process from concept to publication.Guideline Initiatives
See ASTRO's guidelines in development, including collaborations with other organizations, as well as a list of potential future topics.
Clinical Practice Guidelines
Guidelines are "Statements that include recommendations intended to optimize patient care that are informed by a systematic review of evidence and an assessment of the benefits and harms of alternative care options" as defined by the National Academy of Medicine (formerly Institute of Medicine).
Partial Breast Irradiation for Patients with Early-Stage Invasive Breast Cancer or Ductal Carcinoma In Situ (ASTRO) – 2023
Management of Hereditary Breast Cancer (ASCO/ASTRO/SSO) – 2020
Margins for Breast-Conserving Surgery With Whole-Breast Irradiation in Ductal Carcinoma in Situ (SSO/ASTRO/ASCO) – 2016/Affirmed 2019
Radiation Therapy for the Whole-Breast (ASTRO) – 2018
Autologous Breast Reconstruction with DIEP or Pedicled TRAM Abdominal Flaps Autologous Breast Reconstruction with DIEP or Pedicled TRAM Abdominal Flaps (ASPS) – 2017 ASTRO endorsement
Postmastectomy Radiotherapy (ASCO/ASTRO/SSO) – 2001/Updated 2016 (update in progress)
Margins for Breast-Conserving Surgery With Whole-Breast Irradiation in Stages I and II Invasive Breast Cancer (SSO/ASTRO) – 2014
Radiation Therapy for WHO Grade 4 Adult-Type Diffuse Glioma (ASTRO) – 2025
Radiation Therapy for IDH-Mutant Grade 2 and Grade 3 Diffuse Glioma (ASTRO) – 2022
Radiation Therapy for Brain Metastases (ASTRO) – 2022
Treatment of Brain Metastases (ASCO/ASTRO/SNO) – 2021
Radiation Therapy for Anal Cancer (ASTRO) – 2025
Radiation Therapy for Rectal Cancer (ASTRO) – 2024
Multimodality Therapy for Locally-Advanced Cancer of the Esophagus or Gastroesophageal Junction-Update (STS/ASTRO) – 2023
External Beam Radiation Therapy for Primary Liver Cancers (ASTRO) – 2021
Radiation Therapy for Pancreatic Cancer (ASTRO) – 2019
Salvage Therapy for Prostate Cancer (AUA/ASTRO/SUO) – 2024
Clinically Localized Prostate Cancer (AUA/ASTRO/SUO) – 2022
Low-Dose-Rate (LDR) Brachytherapy for Primary Treatment of Localized Prostate Cancer: A Systemic Review and Executive Summary of an Evidence-Based Consensus Statement (ABS) – 2021 ASTRO endorsement
Advanced Prostate Cancer Guideline (AUA) – 2020; Amended 2023; Read ASTRO's editorial
Treatment of Non-Metastatic Muscle-Invasive Bladder Cancer (AUA/ASCO/ASTRO/SUO) – 2017/Amended 2020
Diagnosis and Treatment of Early Stage Testicular Cancer Guideline (AUA) – 2019/Amended 2023 ASTRO endorsement
Hypofractionation for Localized Prostate Cancer (ASTRO/ASCO/AUA) – 2018 (replacement in progress)
Radiation Therapy for Endometrial Cancer (ASTRO) – 2022
Radiation Therapy for Cervical Cancer (ASTRO) – 2020
Radiation Therapy for HPV-Positive Oropharyngeal Squamous Cell Carcinoma (ASTRO) – 2024
Guideline on Osteoradionecrosis in Patients with Head and Neck Cancer Treated with Radiation Therapy (ISOO-MASCC-ASCO) – 2024 ASTRO endorsement
External Beam Radiation Therapy for Palliation of Symptomatic Bone Metastases (ASTRO) – 2024
Malnutrition risk screening in adult oncology outpatients: An ASPEN systematic review and clinical recommendations (ASPEN) – 2024 ASTRO Endorsement
Radiation Therapy for Brain Metastases (ASTRO) – 2022
Treatment of Metastatic Carcinoma and Myeloma of the Femur (MSTS/ASTRO/ASCO) – 2020
Palliative Thoracic Radiation Therapy in Lung Cancer (ASTRO) – 2018
Treatment of Oligometastatic Non-Small Cell Lung Cancer (ASTRO/ESTRO) – 2023
Management of Stage III Non-Small-Cell Lung Cancer Guideline (ASCO) – 2021; Read ASTRO's summary; ASTRO Podcast
Radiation Therapy for Small Cell Lung Cancer (ASTRO) – 2020
Palliative Thoracic Radiation Therapy for Non-Small Cell Lung Cancer (ASTRO) – 2011/2018 Update
Stereotactic Body Radiation Therapy (SBRT) for Early-Stage Non-Small Cell Lung Cancer (ASTRO) – 2017
Definitive and Adjuvant Radiation Therapy in Locally Advanced Non-Small Cell Lung Cancer (ASTRO) – 2015 (Outdated guideline has been sunsetted; new guideline coming in 2026)
Endorsements
Guidelines developed by other organizations where ASTRO is invited to participate may be considered for endorsement. ASTRO prefers to have one or more representatives on the task force, to peer review the draft guideline and then to receive a final version for endorsement consideration. All endorsed documents must be approved by ASTRO’s Board of Directors. Once published, a link to the endorsed document is included in the specific disease site listings above. See the collaborative guideline development page for more detail.
