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ASTRO Guideline on Definitive and Adjuvant Radiation Therapy in Non-small Cell Lung Cancer (NSCLC)

Published: June 2015 (Web posted May 2015)
Reaffirmed: 2017

Read Definitive Radiation Therapy Executive Summary
Read Adjuvant Radiation Therapy Executive Summary
Read Full-Text Guideline

This guideline addresses five key questions related to appropriate use of radiation therapy (RT) in the definitive and adjuvant settings for locally advanced non-small cell lung cancer (NSCLC). 1) the ideal radical RT dose fractionation for radiotherapy alone, and 2) for chemoradiation; 3) ideal timing of radical radiotherapy with systemic chemotherapy; 4) indications for postoperative adjuvant RT, and 5) preoperative neoadjuvant RT.

Endorsed by:

American Society of Clinical Oncology

Key Points:

  • Survival rates
  • Local-regional tumor control
  • Regional and distant failure rates
  • Treatment toxicity
  • Response rate


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