ASTRO/ASCO/SSO Guideline on Postmastectomy Radiation Therapy
Published: Web posted September 2025
This multisociety guideline addresses four key questions focusing on radiation therapy (RT) in patients with breast cancer who undergo mastectomy, including (1) indications for PMRT after upfront surgery, (2) indications for PMRT after neoadjuvant systemic therapy followed by surgery, (3) appropriate PMRT treatment volumes and dose-fractionation regimens, and (4) treatment techniques.
Developed in partnership with and endorsed by:
- American Society of Clinical Oncology
- Society of Surgical Oncology
Developed in collaboration with:
- European Society for Radiotherapy and Oncology
Endorsed by:
- American Society of Breast Surgeons
- Royal Australian and New Zealand College of Radiologists
Resources:
- Guideline slide set
- Press release
- Podcast - coming soon
- PMRT pocketcard
