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AUA/ASCO/ASTRO/SUO Guideline on Treatment of Non-Metastatic Muscle-Invasive Bladder Cancer

Published: April 2017 (Amended 2020) 

Read Full-Text Guideline

This multisociety guideline addresses four topics related to the treatment of muscle-invasive bladder cancer that has not metastasized. 1) initial patient evaluation and counseling; 2) recommendations on treatment therapies (neoadjuvant chemotherapy, radical cystectomy, pelvic lymphadectomy and bladder preserving approaches). 3) patient surveillance, follow-up and survivorship; and 4) the role of variant histology for management of urothelial carcinoma.

Developed in collaboration with:

  • American Urological Association
  • American Society of Clinical Oncology
  • American Society for Radiation Oncology
  • Society of Urologic Oncology

Key Points:

  • Initial patient evaluation and counseling
  • Patient surveillance and follow up
  • Bladder preservation


Muscle Invasive Bladder Cancer Algorithm (Amended 2020)
Patient Brochure


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