Radiopharmaceutical Therapy

Radiopharmaceutical therapy (RPT) is a type of personalized medicine that can improve treatment outcomes for patients with certain cancers. While RPT has limited indications currently, its potential applications across many cancer types has spawned growing interest in this modality. Continued investment in research and development in RPT has the potential to yield novel applications as single agents or combined with other drugs, ushering in a new era of tailored and effective cancer therapy. Radiation oncologists with expertise in oncology, radiobiology and physics are well-equipped to provide these treatments to appropriate patients and lead the path forward for the field. ASTRO has been actively developing resources for RPT for many years and continues to advocate for radiation oncology in many ways.

Publications

Through authoritative guidance and multidisciplinary resources, ASTRO defines best practices that advance safe, high‑quality RPT and shape the future of radiation oncology.

• Quality and Safety Considerations for RPT in the Radiation Oncology Environment: An ASTRO Safety White Paper
• A Framework for Patient-Centered Pathways of Care for Radiopharmaceutical Therapy: An ASTRO Consensus Document
• ASTRO's Framework for Radiopharmaceutical Therapy Curriculum Development for Trainees
• RPT-themed ASTROnews issue
• Information on how to become an authorized user for RPT
• Safety White Paper for Radiopharmaceutical Therapy
• RO-ILS Themed Report on Radiopharmaceuticals in Radiation Oncology

Education

ASTRO delivers a comprehensive educational pathway in radiopharmaceutical therapy (RPT), equipping radiation oncology teams with the knowledge, skills and hands‑on experience needed to safely adopt, expand and lead in this rapidly evolving field. From foundational learning to advanced clinical practice, ASTRO’s RPT education supports clinicians at every stage of readiness.

Authorized User (AU) Training Centers

ASTRO’s AU Training Centers offer structured, hands‑on clinical training to help radiation oncologists meet regulatory requirements for Authorized User status. Through expert mentorship and supervised case experience, participants gain practical skills while advancing safe, consistent and high‑quality delivery of radiopharmaceutical therapy. Register now!

Beyond the Beam: RPT Curriculum Series

This nine‑part, on‑demand curriculum integrates radiopharmaceutical therapy into core radiation oncology training, covering radiation biology, medical physics and clinical application. Designed for flexibility and depth, Beyond the Beam delivers comprehensive, practice‑ready education accessible through ASTRO Academy.

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RPT Workshop

Held annually at the ASTRO Annual Meeting, this flagship workshop offers an immersive learning experience led by recognized leaders in RPT. Tailored for radiation oncologists, medical physicists and nuclear medicine physicians, the workshop provides in‑depth insights into radiopharmaceutical science, clinical implementation and emerging innovations. Watch the 2025 recording now.

Quality

ASTRO’s APEx® – Accreditation Program for Excellence offers a dedicated RPT designation for practices aligned with national quality and safety standards. As radiopharmaceutical therapies continue to expand, the APEx RPT designation signals that your practice is ready, demonstrating leadership, credibility and expertise to patients, peers, health systems and pharmaceutical partners. Practices may pursue RPT accreditation as a stand‑alone designation or as part of the comprehensive APEx program.

Take the next step 

Learn more about the APEx RPT designation on the ASTRO blog and discover how accreditation can elevate your RPT program.

Ready to get started or have questions? 

Contact ASTRO staff, to explore eligibility, timelines and next steps.

Radiopharmaceutical Therapy Roundtable

ASTRO is leading the future of radiopharmaceutical therapy by bringing the field together. Since 2023, ASTRO has convened bi-annual meetings with RPT industry leaders alongside academic and community clinicians for a strategic dialogue to shape the direction of RPT.

These discussions directly informed ASTRO’s RPT priorities. With strong engagement and momentum, ASTRO is actively planning the next RPT Roundtable to continue driving collaboration, innovation and leadership in radiopharmaceutical therapy. Learn more about the RPT Roundtable.