Radiotherapeutic and surgical management for newly diagnosed brain metastasis/es

  • Publication
    Online – January 2012
    Print – July 2012

    This guideline includes nine key clinical questions looking at both single and multiple newly diagnosed intraparenchymal brain metastases. It first considers the prognostic factors that can predict survival in recently diagnosed patients and help guide treatment. It then assesses the role of surgery, with and without whole brain radiation therapy (WBRT), in single brain metastases and how surgery compares to radiosurgery in these patient in terms of survival and brain control. The guideline also discusses use of WBRT alone, radiosurgery alone and a combination of the two. Finally, it offers recommendations on combining WBRT with radiosensitizers or chemotherapy.

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    Quick Reference

    • Surgical resection
    • Whole brain radiotherapy (WBRT)
    • Radiosurgery
    • Palliative supportive care
    • Radiosensitizers
    • Chemotherapy

    Resources

    Challenging Cases to CNS Current Approaches
    Managing Brain Metastases in the 21st Century: Treatment Options and Case Discussions

    Author Society
    American Society for Radiation Oncology

    Previous version
    None

    Endorsements
    Congress of Neurological Surgeons

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