Consensus guideline on margins for breast-conserving surgery with whole-breast irradiation in stages I and II invasive beast cancer

  • Publication
    Print – March 2014

    This collaborative guideline considers several questions related to defining margins for patients who have reached breast-conserving surgery and whole breast irradiation. It delineates when margins are positive and the necessary width to consider the margin negative. It also addresses the interaction between margin width and systemic therapy; biologic subtype; radiation therapy technique, fractionation and boost; invasive lobular carcinoma or lobular carcinoma in situ; and young age. 

    Read full guideline

    Quick Reference

    • Risk of ipsilateral breast tumor recurrence (IBTR)
    • IBTR rate
    • Margin width
    • Local failure

    Breast Cancer Refresher - 2017
    Timing of RT and Chemo after BCS for Node-Positive Breast Cancer

    Author Society
    American Society for Radiation Oncology
    Society of Surgical Oncology

    Previous version

    American Society of Breast Surgeons
    American Society of Clinical Oncology

  • Disclaimer

    ASTRO guidelines present scientific, health, and safety information and may reflect scientific or medical opinion. They are available to ASTRO members and the public for educational and informational purposes only. Commercial use of any content in this guideline without the prior written consent of ASTRO is strictly prohibited.