Patient Care and Research

ASTRO Guideline on Radiotherapeutic and Surgical Management for Newly Diagnosed Brain Metastasis(es)

Published:  July 2012 (Web posted January 2012)

Read Full-Text Guideline

This guideline includes nine key questions looking at both single and multiple newly diagnosed intraparenchymal brain metastases. Topics include the prognostic factors that can predict survival in recently diagnosed patients and help guide treatment; the role of surgery, with and without whole brain radiation therapy (WBRT), in single brain metastases and how surgery compares to radiosurgery in these patient in terms of survival and brain control. The guideline also discusses use of WBRT alone, radiosurgery alone and a combination of the two, as well as recommendations on combining WBRT with radiosensitizers or chemotherapy.

Endorsed by:

Congress of Neurological Surgeons

Key Points:

  • Surgical resection
  • Whole brain radiotherapy (WBRT)
  • Radiosurgery
  • Palliative supportive care
  • Radiosensitizers
  • Chemotherapy


Challenging Cases to CNS Current Approaches (CME)
Managing Brain Metastases in the 21st Century: Treatment Options and Case Discussions (CME)
Podcast with guideline chairs
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