Publication Print – August 2013
This collaborative guideline developed recommendations on several questions related to appropriate use of radiation therapy in patients who have undergone prostatectomy, both as adjuvant therapy following surgery and after recurrence. It examines the impact of adjuvant RT on recurrence and survival and how these outcomes are affected by factors such as margin status, seminal vesicle invasion, Gleason score and patient age. For salvage therapy, the guideline also addresses whether RT improves outcomes and whether its effects are limited to certain patient subgroups. In addition, the document considers the question of whether to administer adjuvant RT prior to recurrence or wait and treat patients who recur with salvage RT. Finally, radiation therapy techniques, use of androgen deprivation therapy together with RT and data on
toxicity and quality of life in the post-prostatectomy setting are discussed.
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Resources Challenging Cases in the Management of Newly Diagnosed and Recurrent Prostate Cancer
Author SocietyAmerican Society for Radiation OncologyAmerican Urological Association
EndorsementsAmerican Society of Clinical Oncology