Publication Online – August 2016 Print – January 2017
This guideline update addresses the eight questions from the original bone metastases guideline published in 2011 based on new literature. It first discusses effective fractionation schemes to treat pain and/or prevent morbidity from peripheral bone metastases. Next, it looks at the appropriateness of RT for bone metastases involving the spine and other critical structures and whether there are long-term side effect risks that
should limit use of single fraction RT for bone metastases. In addition, the guideline gives recommendations on retreatment with radiation to both peripheral and spinal bone metastases and the role of highly conformal RT in primary and re-treatment. Finally, the document considers whether surgery, radionuclide, bisphosphonates, or kyphoplasty/vertebroplasty obviate the role of RT in pain bone metastases.
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Resources Palliative Radiation and Supportive OncologyIntroduction to the use of RT for Palliation of Cancer Related DistressASTRO’s SBRT Model Policy
Author SocietyAmerican Society for Radiation Oncology
Previous versionPalliative Radiotherapy for bone Metastases: An ASTRO Evidence-Based Guideline - 2011