QUANTEC: Radiation-Associated Liver Injury
Charlie C. Pan, MD, Brian D. Kavanagh, MD, MPH, Laura A. Dawson, MD, X. Allen
Li, PhD, Shiva K. Das, PhD, Moyed Miften, PhD, and Randall K. Ten Haken, PhD
liver has numerous critical functions, but many types of radiation to the abdomen,
such as treatment of tumors in the lung or distal esophagus, result in exposure
of the liver and the potential for severe damage. The authors describe the
endpoints, time-course, and dose-volume effect of such irradiation. The authors
also discuss the relationship between use of SBRT and the resulting liver dose
and the potential for radiation therapy-induced liver injury and toxicity.
Read the paper.