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Targeting Cancer Care

QUANTEC: Radiation-Associated Liver Injury

Authors: Charlie C. Pan, MD, Brian D. Kavanagh, MD, MPH, Laura A. Dawson, MD, X. Allen Li, PhD, Shiva K. Das, PhD, Moyed Miften, PhD, and Randall K. Ten Haken, PhD 

The liver has numerous critical functions, but many types of radiation to the abdomen, such as treatment of tumors in the lung or distal esophagus, result in exposure of the liver and the potential for severe damage. The authors describe the endpoints, time-course, and dose-volume effect of such irradiation. The authors also discuss the relationship between use of SBRT and the resulting liver dose and the potential for radiation therapy-induced liver injury and toxicity.

Read the paper.


Content last updated 1/12/2012
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